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1

Membrane transporters in drug development

Giacomini, Kathleen M., Huang, Shiew-Mei, Tweedie, Donald J., Benet, Leslie Z., Brouwer, Kim L.R., Chu, Xiaoyan, Dahlin, Amber, Evers, Raymond, Fischer, Volker, Hillgren, Kathleen M.

Journal:

Nature Reviews Drug Discovery

Year:

2010

Language:

english

File:

PDF, 646 KB

english, 2010

2

Metabolism of hydrazine anti-cancer agents

Donald J. Tweedie, John M. Erikson, Russell A. Prough

Journal:

Pharmacology & Therapeutics

Year:

1987

Language:

english

File:

PDF, 1.37 MB

english, 1987

3

Word-Order Transference between Latin and Greek: The Relative Position of the Accusative Direct Object and the Governing Verb in Cassius Dio and Other Greek and Roman Prose Authors

Bernard Frischer, Roger Andersen, Stanley Burstein, Jane Crawford, Ralph Gallucci, Alain Gowing, Donald Guthrie, Michael Haslam, David Holmes, Vasily Rudich, Robert K. Sherk, Ann Taylor, Fiona Tweedie

Journal:

Harvard Studies in Classical Philology

Year:

1999

Language:

english

File:

PDF, 3.14 MB

english, 1999

4

Teaming with Technology at the TSA: An Examination of Trust in Automation’s Influence on Human Performance in Operational Environments

Korbelak, Kristopher, Dressel, Jeffrey, Tweedie, Donald, Wilson, Whitney, Erchov, Simone, Hilburn, Brian

Journal:

Proceedings of the Human Factors and Ergonomics Society Annual Meeting

Year:

2018

Language:

english

File:

PDF, 5.15 MB

english, 2018

5

Contract Therapy: The Renegotiation of Marriage and the Family

Tweedie, Donald

Journal:

Journal of Psychology and Theology

Year:

1973

File:

PDF, 389 KB

1973

6

Discovery of 4-Benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): A Novel HIV-1 Attachment Inhibitor That Interferes with CD4-gp120 Interactions†

Wang, Tao, Zhang, Zhongxing, Wallace, Owen B., Deshpande, Milind, Fang, Haiquan, Yang, Zheng, Zadjura, Lisa M., Tweedie, Donald L., Huang, Stella, Zhao, Fang

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 62 KB

english, 2003

7

Expression and Characterization of Canine Cytochrome P450 2D15

Fabienne Roussel, David B. Duignan, Michael P. Lawton, R.Scott Obach, Christine A. Strick, Donald J. Tweedie

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 170 KB

english, 1998

8

Molecular Cloning, Expression, and Characterization of CYP2D17 from Cynomolgus Monkey Liver

Dayna C. Mankowski, Kevin J. Laddison, Pamela A. Christopherson, Sean Ekins, Donald J. Tweedie, Michael P. Lawton

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

9

Differential effects of phenobarbitone and 3-methylcholanthrene induction on the hepatic microsomal metabolism of the β-carbolines harmine and harmol

Donald J. Tweedie, M. Danny Burke

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 971 KB

english, 1983

10

Effects of induction on the metabolism and cytochrome P-450 binding of harman and other β-carbolines

Tweedie, Donald J., Prough, Russell A., Burke, M. Danny

Journal:

Year:

1988

Language:

english

File:

PDF, 689 KB

english, 1988

11

[Methods in Molecular Biology] Enzyme Kinetics in Drug Metabolism Volume 1113 ||

Nagar, Swati, Argikar, Upendra A., Tweedie, Donald J.

Year:

2014

Language:

english

File:

PDF, 10.93 MB

english, 2014

12

[Methods in Molecular Biology] Enzyme Kinetics in Drug Metabolism Volume 1113 || Consideration of the Unbound Drug Concentration in Enzyme Kinetics

Nagar, Swati, Argikar, Upendra A., Tweedie, Donald J.

Year:

2014

Language:

english

File:

PDF, 434 KB

english, 2014

13

[Methods in Molecular Biology] Enzyme Kinetics in Drug Metabolism Volume 1113 || Enzyme Kinetics of Oxidative Metabolism: Cytochromes P450

Nagar, Swati, Argikar, Upendra A., Tweedie, Donald J.

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

14

Twenty-second Annual Report of the Almoners,

Barlow, Thomas, Macalister, Donald, Squire Sprigge, S., Butlin, HenryT., Tweedy, John

Journal:

Year:

1911

Language:

english

File:

PDF, 207 KB

english, 1911

15

THE BOARD OF EDUCATION AND THE TEACHING OF HYGIENE

Heron, G.A., Clifford Allbutt, T., Bruce, G.L., Heron, G.A., Macalister, Donald, Osler, William, Tweedy, John

Journal:

Year:

1906

Language:

english

File:

PDF, 393 KB

english, 1906

16

Seventeenth Annual Report of the Almoners,

Powell, R.Douglas, Macalister, Donald, Wakley, Thomas, Tweedy, John, Wakley, Thomas

Journal:

Year:

1906

Language:

english

File:

PDF, 212 KB

english, 1906

17

The Approach to Music

Donald N. Tweedy

Journal:

The Musical Quarterly

Year:

1922

Language:

english

File:

PDF, 233 KB

english, 1922

18

Recent Developments in Queueing

David Y. Burman, Donald R. Smith, Ralph L. Disney, Jagadeesh Chandramohan, William A. Massey, Marcel F. Neuts, E. Arjas, P. Haara, R. L. Tweedie, J. S. Baras, A. J. Dorsey, A. M. Makowski, Jos H. A. D

Journal:

Advances in Applied Probability

Year:

1984

Language:

english

File:

PDF, 489 KB

english, 1984

19

Uptake and metabolism of N,N-dimethyl-2,2-diphenylacetamide in resistant and susceptible plants

Schultz, Donald P., Tweedy, B. G.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1971

Language:

english

File:

PDF, 536 KB

english, 1971

20

Effect of light and humidity on absorption and degradation of diphenamide in tomatoes

Schultz, Donald P., Tweedy, B. G.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1972

Language:

english

File:

PDF, 379 KB

english, 1972

21

Natural Resource Damages for Climate Change—An Idea Whose Time Is Not Yet Come, Part I: NRD Claims Are Not Currently Viable under CERCLA

Gottlieb, Ira, Donald, J. Wylie, Tweedie, Jameson A. L.

Journal:

Environmental Claims Journal

Year:

2008

Language:

english

File:

PDF, 131 KB

english, 2008

22

[Methods in Molecular Biology] Enzyme Kinetics in Drug Metabolism Volume 1113 || Principles and Experimental Considerations for In Vitro Transporter Interaction Assays

Nagar, Swati, Argikar, Upendra A., Tweedie, Donald J.

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

23

[Methods in Molecular Biology] Enzyme Kinetics in Drug Metabolism Volume 1113 || Case Study 5. Deconvoluting Hyperbilirubinemia: Differentiating Between Hepatotoxicity and Reversible Inhibition of UGT1A1, MRP2, or OATP1B1 in Drug Development

Nagar, Swati, Argikar, Upendra A., Tweedie, Donald J.

Year:

2014

Language:

english

File:

PDF, 363 KB

english, 2014

24

[Methods in Molecular Biology] Enzyme Kinetics in Drug Metabolism Volume 1113 || Rationalizing Underprediction of Drug Clearance from Enzyme and Transporter Kinetic Data: From In Vitro Tools to Mechanistic Modeling

Nagar, Swati, Argikar, Upendra A., Tweedie, Donald J.

Year:

2014

Language:

english

File:

PDF, 496 KB

english, 2014

25

THE APPROACH TO MUSIC

TWEEDY, DONALD N.

Journal:

The Musical Quarterly

Year:

1922

Language:

english

File:

PDF, 363 KB

english, 1922

26

Unexpected interaction between CYP3A4 and BI 11634: is BI 11634 interacting with CYP3A4 similar to nifedipine?

Mathur, Arti, Tweedie, Donald J., Maw, Holly Hlaing-Hlaing, Li, Yongmei

Journal:

Drug Metabolism and Drug Interactions

Year:

2013

Language:

english

File:

PDF, 802 KB

english, 2013

27

Sex-, Species-, and Tissue-Specific Metabolism of Empagliflozin in Male Mouse Kidney Forms an Unstable Hemiacetal Metabolite (M466/2) That Degrades to 4-Hydroxycrotonaldehyde, a Reactive and Cytotoxic Species

Taub, Mitchell E., Ludwig-Schwellinger, Eva, Ishiguro, Naoki, Kishimoto, Wataru, Yu, Hongbin, Wagner, Klaus, Tweedie, Donald

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 769 KB

english, 2015

28

Circumpolar Arctic Tundra Vegetation Change Is Linked to Sea Ice Decline

Bhatt, Uma S., Walker, Donald A., Raynolds, Martha K., Comiso, Josefino C., Epstein, Howard E., Jia, Gensuo, Gens, Rudiger, Pinzon, Jorge E., Tucker, Compton J., Tweedie, Craig E., Webber, Patrick J.

Journal:

Earth Interactions

Year:

2010

Language:

english

File:

PDF, 5.40 MB

english, 2010

29

Challenges and solutions to metabolites in safety testing: impact of the International Conference on Harmonization M3(R2) guidance

Yu, Hongbin, Bischoff, Daniel, Tweedie, Donald

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2010

Language:

english

File:

PDF, 496 KB

english, 2010

30

AIP Conference Proceedings [AIP REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION: Volume 30A; Volume 30B - San Diego, California, (USA) (18–23 July 2010)] - FINITE ELEMENT ANALYSIS OF ULTRASONIC PHASED ARRAY INSPECTIONS ON ANISOTROPIC WELDS

Harvey, G., Tweedie, A., Carpentier, C., Reynolds, P., Thompson, Donald O., Chimenti, Dale E.

Year:

2011

Language:

english

File:

PDF, 399 KB

english, 2011

31

Incorporation of Atrazine Side-Chain into Amino Acids of Corn

Donald P. Schultz and B. G. Tweedy

Journal:

Year:

1971

Language:

english

File:

PDF, 457 KB

english, 1971

32

Abnormal Lymphatic Channels Detected by T2-Weighted MR Imaging as a Substrate for Ventricular Arrhythmia in HCM

Kolman, Louis, Welsh, Donald G., Vigmond, Edward, Joncas, Sebastien X., Stirrat, John, Scholl, David, Rajchl, Martin, Tweedie, Edward, Mikami, Yoko, Lydell, Carmen, Howarth, Andrew, Yee, Raymond, Whit

Journal:

Journal of the American College of Cardiology: Cardiovascular Imaging

Year:

2016

Language:

english

File:

PDF, 530 KB

english, 2016

33

Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P-gp Inhibition

Chu, Xiaoyan, Galetin, Aleksandra, Zamek-Gliszczynski, Maciej J., Zhang, Lei, Tweedie, Donald J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 350 KB

english, 2018

34

Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac

Chan, Tom S., Yu, Hongbin, Moore, Amanda, Khetani, Salman R., Tweedie, Donald

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 829 KB

english, 2019

35

Divergence between genes but limited allelic polymorphism in two MHC class II A genes in Leach’s storm-petrels Oceanodroma leucorhoa

Rand, Laura M., Woodward, Carla, May, Rose, Ackerman, Ross A., Tweedie, Bridget, Zicarelli, T. Bruno, Dearborn, Donald C.

Journal:

Year:

2019

Language:

english

File:

PDF, 1020 KB

english, 2019

36

Perspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A Substrates

Ramsden, Diane, Fung, Conrad, Hariparsad, Niresh, Kenny, Jane R., Mohutsky, Michael, Parrott, Neil J., Robertson, Sarah, Tweedie, Donald J.

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1.38 MB

english, 2019

37

Divergence between genes but limited allelic polymorphism in two MHC class II A genes in Leach’s storm-petrels Oceanodroma leucorhoa

Rand, Laura M., Woodward, Carla, May, Rose, Ackerman, Ross A., Tweedie, Bridget, Zicarelli, T. Bruno, Dearborn, Donald C.

Journal:

Year:

2019

File:

PDF, 1020 KB

2019

38

Perspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A Substrates

Ramsden, Diane, Fung, Conrad, Hariparsad, Niresh, Kenny, Jane R., Mohutsky, Michael, Parrott, Neil J., Robertson, Sarah, Tweedie, Donald J.

Journal:

Drug Metabolism and Disposition

Year:

2019

File:

PDF, 1.38 MB

2019

39

Contract Therapy and the Christian Covenant

Tweedie, Donald F.

Journal:

Journal of Psychology and Theology

Year:

1973

File:

PDF, 283 KB

1973

40

Reminiscences of Paul Tournier

Tweedie, Donald F.

Journal:

Journal of Psychology and Theology

Year:

1973

File:

PDF, 167 KB

1973

41

Incorporation of Atrazine Side-Chain into Amino Acids of Corn

Schultz, Donald P., Tweedy, B. G.

Journal:

Year:

1971

File:

PDF, 1.59 MB

1971

42

The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps

Sutherland, Vicki L, McQueen, Charlene A, Mendrick, Donna, Gulezian, Donna, Cerniglia, Carl, Foley, Steven, Forry, Sam, Khare, Sangeeta, Liang, Xue, Manautou, Jose E, Tweedie, Donald, Young, Howard, A

Journal:

Toxicological Sciences

Year:

2020

File:

PDF, 257 KB

2020

43

P118 - Reaction phenotyping of low turnover compounds through persistent inhibition of cytochromes P450 in long term cultures with human hepatopac

Smith, Sheri, Tweedie, Donald, Lyman, Michael, Menzel, Karsten

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2020

File:

PDF, 51 KB

2020

44

Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro CYP Induction Studies Including Impact on Drug Interaction Risk Assessment

Wong, Simon G, Ramsden, Diane, Dallas, Shannon, Fung, Conrad, Einolf, Heidi J., Palamanda, Jairam, Chen, Liangfu, Goosen, Theunis C., Siu, Yin Fai Amy, Zhang, George, Tweedie, Donald J., Hariparsad, N

Journal:

Drug Metabolism and Disposition

Year:

2020

File:

PDF, 2.03 MB

2020